Biofilms, dense microbial communities on medical devices and tissues, are notoriously resistant to antibiotics, causing persistent infections that account for many of chronic cases. Traditional lab methods often miss key aspects of biofilm behavior, including persistence, regrowth, and migration, making it difficult to design...
Skin diseases like atopic dermatitis and psoriasis have been linked to gut health, yet the mechanisms behind this gut–skin connection remain poorly understood. Clinical evidence suggests that an imbalance in gut microbes (dysbiosis) can disrupt the intestinal barrier, leading to skin inflammation. However, it...
Red blood cell (RBC) deformability, the ability of RBCs to squeeze through tiny capillaries, is critical for oxygen delivery and cell longevity. While it is known that RBC deformability changes in many diseases, its behavior in iron deficiency (ID), particularly before the onset of...
Precise diagnosis of infectious diseases is often hindered by a lack of accessible biomarkers that can distinguish between active and past infections. While antibody levels are commonly measured, they typically fail to provide this distinction, especially in endemic contexts where antibodies can persist long...
Chimeric antigen receptor T-cell (CAR-T) therapy has reshaped the treatment landscape for hematologic cancers, but the process of manufacturing CAR-T cells remains a major bottleneck. Traditional protocols might stretch over 9 days and risk shifting T-cell populations toward terminally differentiated phenotypes, depleting the naive-like...