Cancer research Tag

An integrated microfluidic chip for isolation, culture and drug susceptibility testing of cancer cells

Abstract "Cancer patients with advanced disease are characterized by intrinsic challenges in predicting drug response patterns, often leading to ineffective treatment. Current clinical practice for treatment decision-making is commonly based on primary or secondary tumour biopsies, yet when disease progression accelerates, tissue biopsies are not performed...

Dynamic morphological transformation studies using microfluidics

3D morphable structures employed in microfluidic research

Abstract "The geometric reconfigurations in three-dimensional morphable structures have a wide range of applications in flexible electronic devices and smart systems with unusual mechanical, acoustic, and thermal properties. However, achieving the highly controllable anisotropic transformation and dynamic regulation of architected materials crossing different scales remains challenging....

Anticancer, microfluidic BH3

Anticancer precision medicine fostered by microfluidic technology

Abstract "Precision medicine is starting to incorporate functional assays to evaluate anticancer agents on patient-isolated tissues or cells to select for the most effective. Among these new technologies, dynamic BH3 profiling (DBP) has emerged and extensively been used to predict treatment efficacy in different types of...