March 2022

Microfluidic measurement of minimum inhibitory concentration

31 Mar

Microfluidic quantification of bacterial single-cell motility can be used as a proxy for bacterial heteroresistance

https://www.youtube.com/watch?v=XHOmBV4js_E One of the most promising applications of microfluidics technology has been proven to be the single-cell analysis. Hardly a week goes by without a new microfluidic development for microfluidic single-cell analysis. Over the nearly past decade, the field has accelerated at a high rate...

11:46 / Latest Research

microfluidic chip to study human trophoblast invasion during implantation

26 Mar

A microenigneered system models multicellular events in early pregnancy

Abstract"Successful establishment of pregnancy requires adhesion of an embryo to the endometrium and subsequent invasion into the maternal tissue. Abnormalities in this critical process of implantation and placentation lead to many pregnancy complications. Here we present a microenigneered system to model a complex sequence of...

11:12 / Latest Research

microfluidics: bottom up neuroscience with microfluidic

23 Mar

Microfabricated structures enable the formation of an in vitro neural network

Abstract "Bottom-up neuroscience, which consists of building and studying controlled networks of neurons in vitro, is a promising method to investigate information processing at the neuronal level. However, in vitro studies tend to use cells of animal origin rather than human neurons, leading to conclusions that...

17:49 / Latest Research

Dropseq microfludic chips for analyzing rna velocity

19 Mar

Cellular transcriptomic vector fields revealed using dropseq microfluidic chips

RNA velocity is a vector that is employed for predicting the future state of the cells. Here, researchers used dropseq microfluidic chips for single-cell RNA sequencing along with RNA velocity and metabolic labelling to introduce a platform called dynamo to predict cell fates. Summary "Single-cell (sc)RNA-seq, together...

13:10 / Latest Research

microfluidics for crispr analysis

17 Mar

Droplet microfluidics enables high-throughput CRISPR-based gene editing and screening

Abstract "We present a droplet-based microfluidic system that enables CRISPR-based gene editing and high-throughput screening on a chip. The microfluidic device contains a 10 × 10 element array, and each element contains sets of electrodes for two electric field-actuated operations: electrowetting for merging droplets to mix reagents and...

09:38 / Latest Research

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