Organ on a chip Tag

Microfluidic chip for mammalian cell culture
29 Sep

Open source microfluidics for spatio-temporal regulation of microenvironment for mammalian cell cultures

Abstract "Microfluidic-based cell culture allows for precise spatio-temporal regulation of microenvironment, live cell imaging and better recapitulation of physiological conditions, while minimizing reagents’ consumption. Despite their usefulness, most microfluidic systems are designed with one specific application in mind and usually require specialized equipment and expertise for...

16:55 / Latest Research
vascularized immune-competent skin-on-chip platform
22 Sep

Vascularized skin-on-chip for modeling HSV infection

Abstract "Herpes simplex virus (HSV) naturally infects skin and mucosal surfaces, causing lifelong recurrent disease worldwide, with no cure or vaccine. Biomimetic human tissue and organ platforms provide attractive alternatives over animal models to recapitulate human diseases. Combining prevascularization and microfluidic approaches, we present a vascularized,...

17:02 / Latest Research
09 Jun

Microphysiological in vitro platform for studying sarcopenia

Abstract "Microphysiological systems (MPS), also referred to as tissue chips, incorporating 3D skeletal myobundles are a novel approach for physiological and pharmacological studies to uncover new medical treatments for sarcopenia. We characterize a MPS in which engineered skeletal muscle myobundles derived from donor-specific satellite cells that...

10:35 / Latest Research