Organ-on-a-chip microfluidic devices are well known for their abilities in mimicking in vivo conditions and their superiority in drug toxicity screening compared to regular cell culture models. In this week's research highlight, we will introduce another organ-on-chip that takes advantage of microfluidics technology to mimic...
"Microhabitat conditions determine the magnitude and speed of microbial processes but have been challenging to investigate. In this study we used microfluidic devices to determine the effect of the spatial distortion of a pore space on fungal and bacterial growth, interactions, and substrate degradation. The...
"Current equipment and methods for preparation of radiopharmaceuticals for positron emission tomography (PET) are expensive and best suited for large-scale multi-doses batches. Microfluidic radiosynthesizers have been shown to provide an economic approach to synthesize these compounds in smaller quantities, but can also be scaled to...
Neuromuscular junctions (NMJs) are the synaptic junctions between motor neurons (MNs) and muscle fibres and are of crucial importance in delivering signals associated with motor activities. Therefore, defects in the motor neurons or disruption in the activity of NMJs can lead to neurodegenerative diseases such...
"Low-temperature biopreservation and 3D tissue engineering present two different routes towards eventual on-demand access to transplantable biologics, but recent advances in both fields present critical new opportunities for crossover between them. With help of microfluidics, in this work, we demonstrate sub-zero centigrade preservation and revival...