Droplet microfluidic Tag

Droplet microfluidics for biomolecular condensate phase diagrams

Abstract "The assembly of biomolecules into condensates is a fundamental process underlying the organisation of the intracellular space and the regulation of many cellular functions. Mapping and characterising phase behaviour of biomolecules is essential to understand the mechanisms of condensate assembly, and to develop therapeutic strategies...

Microfluidic quantification of heterogeneity of bacterial populations

Microfluidic quantification of heterogeneity of bacterial populations

Abstract "Severe non-healing infections are often caused by multiple pathogens or by genetic variants of the same pathogen exhibiting different levels of antibiotic resistance. For example, polymicrobial diabetic foot infections double the risk of amputation compared to monomicrobial infections. Although these infections lead to increased morbidity...