"Low-temperature biopreservation and 3D tissue engineering present two differing routes towards eventual on-demand access to transplantable biologics, but recent advances in both fields present critical new opportunities for crossover between them. In this work, we demonstrate sub-zero centigrade preservation and revival of autonomously beating three-dimensional...
Myocardial infarction, commonly known as heart attack, causes a majority of cardiovascular disease (CVD) deaths which can be triggered by occlusion of the arteries. Finding new drugs to fight myocardial infractions requires accurate modelling of the process. In a recent article published in the lab...
"Droplets microfluidics is broadening the range of Lab on a Chip solutions that, however, still suffer from the lack of an adequate level of integration of optical detection and sensors. In fact, droplets are currently monitored by imaging techniques, mostly limited by time-consuming data post-processing...
Since its emergence as a model organism, Caenorhabditis elegans (C. elegans), has appeared as a powerful means for studying a broad range of topics ranging from developmental biology to neuroscience. Having many genes with functional counterparts in humans, a transparent body, a short life cycle...
"Mammary tumor organoids have become a promising in vitro model for drug screening and personalized medicine. However, the dependency on the basement membrane extract (BME) as the growth matrices limits their comprehensive application. In this work, mouse mammary tumor organoids are established by encapsulating tumor...