The Blood-Brain Barrier (BBB) is a highly selective membrane that separates the blood flow from the bulk of the brain and the central nervous system. This membrane is semi-permeable and ensures that the brain maintains its functionality by blocking unwanted molecules and ions from entering...
The majority of microfluidic devices for Assisted Reproductive Technologies (ART) have aimed at enhancing sperm selection and analysis so far. A novel microfluidic chip, however, turns the page by offering a more efficient protocol for oocyte cryopreservation. The design rationale and performance of this microfluidic...
Researchers at the University of Leeds have developed a microfluidic platform for evaluating microbubble-assisted drug delivery to spheroids. The microfluidic technology helped in creating a physiologically relevant in vitro condition for trapping and culturing tumor spheroids and subjecting them to microbubble guided drug delivery. The...
Tissue slices are precision-cut organ slices that are commonly used for metabolism and toxicity research due to their advantages such as maintaining cell-type diversity and preserving the organ cytostructure as well as the metabolic enzymes. A major issue is that the tissues are mostly single-use in...
Microfluidic single-cell analysis platforms often take advantage of droplet microfluidic for encapsulating the cells within nL-pL droplets at high throughputs. Depending on the target outcome (genomics, epigenomics, transcriptomics, etc.), specific protocols are available for the tests. Cells in a culture can be highly heterogeneous and impose...