As droplet microfluidics progresses, more sophisticated applications get developed by researchers which in turn require more complex techniques for manipulation. One class of such droplets is endoskeletal droplets. Endoskeletal droplets are complex colloids in which a solid phase is cast within a liquid emulsion. This...
"Multiple myeloma (MM) is an incurable B cell malignancy characterized by the accumulation of monoclonal abnormal plasma cells in the bone marrow (BM). It has been a significant challenge to study the spatiotemporal interactions of MM cancer cells with the embedded microenvironments of BM. Here...
Recent technological developments including microfluidics have facilitated genome-wide transcriptional profiling in select brain regions. These studies can be employed to discover correlations between altered transcriptional activity across brain regions with stress-related mood disordered leading to a better understanding of the molecular underlying driving mechanisms. Here,...
"Biomedical research relies on identification and isolation of specific cell types using molecular biomarkers and sorting methods such as fluorescence or magnetic-activated cell sorting. Labelling processes potentially alter the cells’ properties and should be avoided, especially when purifying cells for clinical applications. A promising alternative...
Stand-alone microfluidic devices have been shown great promises over the past few decades in simplifying biological as well as chemical assays. However, in many applications, the processes cannot be reduced into a single task and require multiple tasks to be conducted sequentially. In this week's...