Understanding how sperm reach the egg is still one of the most fascinating problems in reproductive biology. Inside the female reproductive tract, sperm face a highly structured and fluid-rich environment filled with narrow passages, folds, and mucus-like fluids. While hyperactivation, a change in swimming...
Assessing which embryos have the highest chance of successful implantation remains a major challenge in assisted reproduction. Current clinical practice relies heavily on morphological grading, which is subjective and often fails to accurately predict developmental potential. While metabolite analysis of embryo culture media offers...
Continuous glucose monitoring plays a central role in diabetes management, especially for patients with type 1 diabetes. Current systems typically rely on enzyme-based electrochemical sensors that measure glucose in interstitial fluid. A recent microfluidic study explores a different strategy by using living pancreatic islets...
Organoids have transformed in vitro tissue modeling, but their culture remains labor-intensive and variable. Manual media exchange, orbital shakers, and dependence on humidified CO₂ incubators make continuous monitoring difficult and introduce experimental inconsistencies. Although microfluidic systems improve media exchange and reproducibility, most still rely...
Spatial biology increasingly depends on technologies that can map gene expression and protein localization directly within intact tissues. However, many existing spatial omics workflows rely on separate assays performed on adjacent sections, which introduces alignment errors and limits true multimodal integration. As the authors...