Droplet microfluidic Tag

microfluidic analysis of peptides

Microfluidic analysis of peptides reveals a correlation between physio-chemical properties and biological activity

"Antimicrobial resistance challenges the ability of modern medicine to contain infections. Given the dire need for new antimicrobials, polypeptide antibiotics hold particular promise. These agents hit multiple targets in bacteria starting with their most exposed regions—their membranes. However, suitable approaches to quantify the efficacy of...

Dropseq chips help researchers to study the transcriptional mechanisms of stress-related mood disorder major depression

Recent technological developments including microfluidics have facilitated genome-wide transcriptional profiling in select brain regions. These studies can be employed to discover correlations between altered transcriptional activity across brain regions with stress-related mood disordered leading to a better understanding of the molecular underlying driving mechanisms. Here,...

Microfluidic deep mutational scanning

Droplet microfluidics for deep mutational scanning

A droplet microfluidic chip is developed as a part of a platform for deep mutational scanning of human executioner caspases. "The human caspase family comprises 12 cysteine proteases that are centrally involved in cell death and inflammation responses. The members of this family have conserved sequences...