Organoids have transformed in vitro tissue modeling, but their culture remains labor-intensive and variable. Manual media exchange, orbital shakers, and dependence on humidified CO₂ incubators make continuous monitoring difficult and introduce experimental inconsistencies. Although microfluidic systems improve media exchange and reproducibility, most still rely...
Recent advancements in the field of tissue engineering have yielded a novel culture system that significantly enhances the fabrication of human cardiac tissues. This system integrates a microfluidic platform with a heart extracellular matrix (HEM) hydrogel, designed to foster the maturation of tissues that more closely...
Dry Eye Syndrome (DES) presents a significant challenge in ocular health, impacting millions globally with symptoms that reduce quality of life. Traditional research methods have fallen short in replicating the complex interplay at the corneal surface under DES conditions. A novel microfluidic study involving an...
Recent advancements in tissue engineering and organ-on-chip technology have led to the development of a novel microfluidic platform designed for the encapsulation and long-term culture of various types of cell aggregates with an emphasis on vascularization. This microfluidic chip represents a step forward in addressing...
Fluid flow through a porous media can be seen in many biological and geological systems. The pores in porous media induce very complex fluid patterns that are sometimes overlooked. For example, the complex morphology in these systems is often associated with dead-ends resulting in a...