Spatial biology increasingly depends on technologies that can map gene expression and protein localization directly within intact tissues. However, many existing spatial omics workflows rely on separate assays performed on adjacent sections, which introduces alignment errors and limits true multimodal integration. As the authors...
Microfluidic devices are widely used to replicate the physical constraints bacteria experience in natural and host-associated environments. However, even with advanced microfluidic confinement, it has remained unclear how motile bacteria generate propulsion when channel dimensions approach the size of the cell itself. This question...
Understanding how brain tumors interact with surrounding neural circuits is a significant challenge in neuro-oncology. The real-time electrical dialogue between neurons and tumor cells has been difficult to capture and interpret with existing tools. A recent microfluidic chip reported in a study titled “A...
Timely identification of infectious pathogens remains a major bottleneck in clinical care, particularly in conditions such as sepsis or complicated urinary tract infections where every hour of delay can worsen outcomes. Conventional diagnostics rely on culture-based workflows that often take days, struggle with low...
Early diagnosis of sickle cell disease remains a major challenge, particularly in low-resource settings where access to centralized laboratories is limited. Conventional diagnostic techniques such as hemoglobin electrophoresis or HPLC are accurate but require expensive equipment, trained personnel, and long processing times. This gap...